Esophageal Sphincter Histology Biology Diagrams The lower esophageal sphincter is a valve between your esophagus and stomach. It prevents stomach contents from going back up the esophagus.

Upper esophageal sphincter is composed of all skeletal muscles and lower esophageal sphincter of all smooth muscles. Based on the studies in mice embryo, esophagus is comprised of entirely smooth muscles at the beginning that slowly transdifferentiate into the skeletal muscles during later embryological age until few days after birth [54]. Esophagus: Anatomy & Physiology Anatomy Layers Mucosa (Squamous Epithelium) Submucosa Muscularis Propria (Longitudinal) Upper 1/3: Striated Lower 2/3: Smooth No Serosa Importance: CA Spreads Through Lymphatics Sphincters Upper Esophageal Sphincter (UES) Cricopharyngeus Muscle 15 cm From Incisors Most Common Site of Iatrogenic Perforation and Foreign Body Prevents Air Swallowing Innervation
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The Oesophagus Biology Diagrams
Lower esophageal sphincter Distal 2-4 cm esophageal high pressure zone defined by manometry. Corresponds to vestibule on esophagram. Prevents gastroesophageal reflux. Drugs and many types of food and drink affect lower esophageal sphincter and can lead to reflux. Glucagon relaxes the lower esophageal sphincter when used for air-contrast upper gastrointestinal examination. The tubular esophagus

There are two sphincters present in the oesophagus, known as the upper and lower oesophageal sphincters. They act to prevent the entry of air and the reflux of gastric contents respectively. Upper Oesophageal Sphincter The upper sphincter is an anatomical, striated muscle sphincter at the junction between the pharynx and oesophagus.

Esophagus I: anatomy, rings, inflammation Biology Diagrams
The lower esophageal sphincter (LES), also termed the cardiac sphincter and cardioesophageal sphincter, is located slightly more than an inch (about 3 cm) proximally from where the esophagus meets the stomach. Similar to the UES, the LES is normally contracted and closed, primarily preventing stomach contents from entering the esophagus body.
